Manchester United moved back into the top four after beating Southampton, while the north London derby ended in a draw.
Pierre-Emerick Aubameyang saw a last-gasp penalty saved as Arsenal drew 1-1 against Tottenham to leave Spurs four points ahead of their north London rivals in the top-four race.
Aaron Ramsey, playing in his final north London derby before leaving to join Juventus in the summer, finished on the counter-attack after 16 minutes to put the Gunners ahead.
Spurs levelled from the penalty spot in the 74th minute through Harry Kane after he had been barged over by Shkodran Mustafi.
Arsenal might have been aggrieved as Kane was offside before he was fouled, but they spurned the chance to snatch victory when Lloris saved Aubameyang’s penalty in the 89th minute and Jan Vertonghen blocked the follow-up shot on the line.
Riyad Mahrez scored the only goal of the game as Manchester City beat Bournemouth to return to the top of the Premier League table.
It was a far-from-vintage performance from City, who faced a well-drilled Bournemouth defence, but Mahrez slotted home in the 55th minute to hand the visitors the win.
Pep Guardiola was dealt a blow, though, as Kevin De Bruyne was forced to come off just before the break after picking up another injury, with the manager saying after the game that it was “muscular”.
City go two points clear of Liverpool – who play Everton today, at the top of the Premier League while Bournemouth remain in 12th and winless in five league outings.
Brighton won their first game of 2019 after narrowly overcoming Premier League strugglers Huddersfield 1-0 at the Amex Stadium on Saturday.
Substitute Florin Andone’s close-range header in the 79th minute proved the difference to end the hosts’ seven-game winless streak.
Brighton came close to scoring in the first half through Alireza Jahanbakhsh, but his effort cracked off the crossbar. In the second half, Andone was denied by a fine stop from Jonas Lossl seven minutes before he scored the game’s only goal.
A deserved victory for Chris Hughton’s side means they sit in 15th on 30 points. Huddersfield lie in 20th, 13 points off safety with nine games of the season to go.
Crystal Palace moved eight points clear of relegation trouble after an impressive 3-1 victory over Burnley at Turf Moor.
Jeff Schlupp’s cross was turned in by Phil Bardsley against the run of play on 15 minutes before Michy Batshuayi met Aaron Wan-Bissaka’s low ball to flash in a superb second (48) for the visitors.
After a run of eight league games unbeaten, Sean Dyche’s side have now lost two in succession, with Wilfried Zaha’s trademark finish (76) putting the seal on another deserved away success.
Ashley Barnes headed in a consolation from Ashley Westwood’s cross (90), but the Clarets remain in relegation trouble, five points above 18th-placed Cardiff with Palace sitting in 13th position.
Romelu Lukaku’s second-half double, including a late winner, saw Manchester United come from behind to beat Southampton 3-2 and maintain their top-four hopes.
The Saints took the lead midway through the first half when Yan Valery strode forward and unleashed a 30-yard drive that flew past a startled David de Gea at his near post for his first goal for the club.
However, the home side responded with goals from Andreas Pereira (53) and Lukaku (59) before the hour-mark, only for Southampton to hit back through James Ward-Prowse’s delicious free kick 15 minutes from time.
But Lukaku was on hand to snatch United a vital victory with just two minutes to go, before Paul Pogba’s late penalty was kept out by Angus Gunn’s outstretched foot.
Wolves scored twice in as many minutes to leave Cardiff deep in relegation trouble with a 2-0 win at Molineux.
Diogo Jota netted a goal-of-the-season contender in the 16th minute after a flowing move involving Morgan Gibbs-White and Raul Jimenez.
Benfica loanee Jimenez doubled the lead on 18 minutes having been teed up by the unselfish Jota, following Sol Bamba’s error.
The result cements seventh place for Wolves, while Cardiff remain two points from safety in 18th after a third Premier League defeat in a row.
West Ham moved up to ninth in the Premier League table with a comfortable 2-0 win over Newcastle at London Stadium.
Declan Rice headed his second-ever West Ham goal into the net in the seventh minute to give his side a lead they never really looked like relinquishing.
Then, after Javier Hernandez had been fouled in the penalty area in the 42nd minute, Mark Noble converted his 22nd Premier League penalty to put the hosts well in command.
Newcastle rallied after the break, but rarely threatened until late on, with Salomon Rondon denied by smart Lukasz Fabianski save, as West Ham saw out the win that sees them leapfrog Everton into ninth, having played a game more, while Newcastle drop to 14th after their first defeat in four. – Sky Sports.
