Liverpool saw their hopes of achieving a record Premier League points total extinguished at Arsenal as two errors resulted in a 2-1 loss for the champions.
The Reds needed at least a point to remain in with a chance of equalling Manchester City’s 100-point haul from two seasons ago, and their hopes of reaching 102 were boosted by Sadio Mane’s opener.
However, uncharacteristic gaffes from Virgil van Dijk and then goalkeeper Alisson saw the Gunners come from behind as they put Sunday’s defeat to rivals Tottenham behind them.
Alexandre Lacazette equalised and Reiss Nelson scored his first Premier League goal to leave Liverpool on 93 points with just two games remaining.
There was an early warning regarding Emiliano Martinez’s clearances when Roberto Firmino charged down one of his attempts and blocked the ball onto a post.
Ten minutes later, Martinez was harried again and Liverpool won the ball back from his kick, with Firmino releasing Andy Robertson to slide across for Mane, whose first-time finish gave the Reds a 20th-minute lead.
However, Arsenal quickly turned the game around following mistakes from Van Dijk and then Alisson.
First, Van Dijk, under pressure from Nelson, played a loose pass between Fabinho and Alisson, allowing Lacazette to capitalise for the equaliser.
Alisson was the next to sloppily give away possession, Lacazette again seizing upon the ball and squaring for Nelson to give the Gunners the lead prior to the interval.
Liverpool almost hit back early in the second period when Mohamed Salah, making his 150th appearance for the club, sat down David Luiz with a dummy before prodding towards goal only to see Martinez tip over the crossbar.
Jurgen Klopp called for Takumi Minamino from the bench and, after he dragged one shot wide, the Japan international felt he should have had a penalty when Kieran Tierney’s pressure on him in the box went unpunished.
Salah then directed a weak header straight at Martinez, Mane fired a great opportunity wide and Trent Alexander-Arnold’s deflected effort was saved as Liverpool saw their chance of becoming centurions pass them by.