Chelsea suffered a third successive Premier League defeat as Marko Arnautovic secured victory for Stoke.
With Jose Mourinho absent as he served a stadium ban, it was left to his backroom staff to oversee the game for the Blues from the dugout.
A lively first half ended goalless, before Arnautovic hooked home.
Pedro hit the post for Chelsea before Loic Remy had a claim for a penalty denied when he challenged for the ball with Jack Butland late on.
It was the first time that Chelsea would suffer three defeats in a row since 1999 and adds to the pressure on beleaguered manager, Mourinho to find a way to turn things around.
And Jesse Lingard scored his first Manchester United goal as Louis van Gaal’s side beat West Brom.
Winger Lingard, 22, curled home from the edge of the box early in the second half to give the hosts the lead.
Substitute Saido Berahino missed a superb opportunity to equalise late on when he headed over from close range.
Juan Mata then made the win safe from the penalty spot late on after Anthony Martial was fouled by Gareth McAuley, who was sent off.
The victory keeps Manchester United fourth in the Premier League, while West Brom are 12th.
It was also a first win in three league games for the hosts, who have not conceded in more than 500 minutes.
Manchester United fans are struggling to warm to Louis van Gaal’s defensive style of football, with chants of “attack, attack, attack” heard at Old Trafford during Tuesday’s Champions League win against CSKA Moscow.
Only the Baggies had attempted fewer shots (109) than Manchester United (110) prior to Saturday’s game, but Van Gaal indicated he had no intention of abandoning his conservative approach by naming two defensive midfielders – Bastian Schweinsteiger and Michael Carrick – in his starting line-up.
The outcome was, perhaps, predictable, as the hosts, for the most part, lacked the creativity to break down their defence-minded visitors. Only one shot on target was registered in the first half, when Martial shot straight at Boaz Myhill.
However, a moment of quality from Lingard changed the game.
The youngster’s goal forced West Brom to abandon their cautious approach, opening up more gaps at the back for the home side to exploit, ultimately leading to the moment when Martial got through on goal in stoppage time, causing McAuley to give away the decisive penalty.
At the King Power Stadium, Jamie Vardy scored for a ninth successive Premier League game as Leicester beat Watford to go level on points with Manchester City and Arsenal at the top of the table.
Vardy got Leicester’s second from the spot, converting after he was tripped by Watford goalkeeper Heurelho Gomes.
Gomes had already gifted Leicester the lead, somehow letting Ngolo Kante’s tame shot slip through.
A Troy Deeney penalty gave Watford hope, but Leicester held on.
It was arguably harsh on the Hornets, who had the better of the first half.
But Leicester once again improved after the break – 17 of their 19 league goals have come in the second half – and took advantage of the errors of Gomes.
Vardy had been kept quiet by an organised Watford defence in the first half and was even the subject of an injury scare after Leicester took the lead.
Jumping to control the ball with no other player around him, Vardy landed awkwardly and was in discomfort as he lay on the ground, holding his groin.
However, after treatment, he produced a moment typical of his stellar season.
Running clear of the Watford defence, he latched on to a through ball and was only stopped by a clumsy challenge from the onrushing Gomes. From the resulting penalty, Vardy smashed high into the net.
Only Ruud van Nistelrooy, with 10, has scored in more successive Premier League games than Vardy, who is part of the England squad for the upcoming friendlies against Spain and France.
And in the first game of the day, Ayoze Perez’s first-half goal earned Newcastle a first away win in 13 Premier League games as they leapfrogged Bournemouth in the table.
Perez scored from Newcastle’s only shot of the first half with Adam Federici failing to stop his tame effort.
The result was very harsh on a dominant Bournemouth, who were denied by a string of brilliant saves from Newcastle goalkeeper Rob Elliot, reports the BBC.
The Cherries, six league games without a win, slip into the bottom three.
Eddie Howe’s side, promoted to the top tier from the Championship last season, could have done little more to win in the game. Newcastle little less.
But the hosts were let down by poor finishing and a man-of-the-match display by Elliot, who denied Joshua King, Dan Gosling and Matt Ritchie.
EPL RESULTS
Stoke 1 – 0 Chelsea
Bournemouth 0 – 1 Newcastle
Leicester 2 – 1 Watford
Man United 2 – 0 West Brom
Norwich 1 – 0 Swansea
Sunderland 0 – 1 Southampton
West Ham 1 – 1 Everton